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Dieta Mediterranea: riduce il rischio di fratture dell’anca da osteoporosi

24/03/2016

Non è tanto l’assunzione dei singoli nutrienti, ma la qualità della dieta, in particolare la dieta mediterranea che protegge dal rischio di fratture dell’anca e dall’osteoporosi le donne in menopausa.

E’ quello che è emerso da un recente studio pubblicato sulla prestigiosa rivista scientifica Jama Internal Medicine basata su dati provenienti da 40 centriclinici degli Stati Uniti inclusi nello studio WHI (Women Health Initiative), condotto su ben 93.676 donne di età compresa tra 50 e 79 anni dal 1998 al 2014.

Le donne che adottavano abitualmente una dieta di tipo mediterraneo sono risultate a minor rischio di osteoporosi e a rischio ridotto di sviluppare fratture dell’anca, altamente invalidanti e in grado di compromettere seriamente la qualità di vita psico-fisica delle donne in menopausa.

Secondo questo studio americano, il consumo di frutta e verdura, cereali integrali, legumi, carni magre e pesce, tipico della dieta mediterranea, oltre a far bene al cuore e al cervello, a proteggere dal cancro, ecc., riduce, seppur leggermente (0,29%), il rischio di incorrere in fratture di quest’osso, l’anca, in tarda età..

“Nonostante la dieta mediterranea non contempli l’assunzione di troppi prodotti lattiero-caseari, fonte di vitamina D e calcio, questo stile alimentare porterebbe comunque a una riduzione del rischio di frattura all’anca”, ha affermato il coordinatore dello studio, il dottor Bernhard Haring, dell’Università di Wurzburg, in Germania.

Questi risultati supportano ulteriorimente il fatto che un modello alimentare sano, seguito abitualmente a partire dalla giovane età, può giocare un ruolo importante anche nel mantenimento della salute delle ossa nelle donne in postmenopausa

Abstract in inglese dell’articolo pubblicato sulla rivista Jama Internal Medicine

Dietary Patterns and Fractures in Postmenopausal Women:  Results From the Women’s Health Initiative 

Bernhard Haring, MD, MPH1; Carolyn J. Crandall, MD, MS2; Chunyuan Wu, MS3; Erin S. LeBlanc, MD, MPH4; James M. Shikany, DrPH5; Laura Carbone, MD6; Tonya Orchard, PhD, RD7; Fridtjof Thomas, PhD8; Jean Wactawaski-Wende, PhD9; Wenjun Li, PhD10; Jane A. Cauley, DrPH11; Sylvia Wassertheil-Smoller, PhD12

1Department of Internal Medicine I, Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Bavaria, Germany
2Department of Medicine, David Geffen School of Medicine, UCLA (University of California at Los Angeles)
3Women’s Health Initiative, Fred Hutchinson Cancer Center, Seattle, Washington
4Kaiser Permanente Center for Health Research Northwest, Portland, Oregon
5Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham
6Department of Medicine, Medical College of Georgia at Georgia Regents University, Augusta
7Human Nutrition Program, Department of Human Sciences, The Ohio State University, Columbus
8Division of Biostatistics and Epidemiology, Department of Preventive Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis
9Department of Epidemiology and Environmental Health, State University of New York at Buffalo
10Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester
11Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania
12Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York

JAMA Intern Med. Published online March 28, 2016. doi:10.1001/jamainternmed.2016.0482

Published online

ABSTRACT

Importance  Considerable efforts have been undertaken to relate single nutrients to bone health. To this point, results are inconsistent. Suboptimal single nutrient intake does not occur in isolation but rather reflects a poor diet quality.

Objective  To assess the association between adherence to a diet quality index constructed on the basis of dietary recommendations or existing healthy dietary patterns and fractures in postmenopausal women.

Design, Setting, and Participants  Post hoc analysis was conducted of longitudinal data from 40 clinical centers throughout the United States included in the Women’s Health Initiative (WHI) observational study. Participants in the prospective cohort included 93 676 women who were eligible for the WHI if they were aged 50 to 79 years. Recruitment was conducted from October 1, 1993, to December 31, 1998, with the study ending August 29, 2014. The WHI food frequency questionnaire was used to derive nutrient and food intake at baseline. Diet quality and adherence were assessed by scores on the alternate Mediterranean Diet (aMED), a 9-category measure of adherence to a Mediterranean dietary pattern; the Healthy Eating Index 2010 (HEI-2010), a 100-point measure of 12 food components; the 11-item Alternate Healthy Eating Index 2010 (AHEI-2010); or the 8-component Dietary Approaches to Stop Hypertension (DASH) diet score.

Main Outcomes and Measures  Outcome measures included incident total and hip fractures. Hazard ratios (HRs) by quintiles of dietary index scores were estimated using Cox proportional hazards regression analyses.

Results  Of the 93 676 participants, 90 014 were included in the analysis (mean [SD] age, 63.6 [7.4]) years. During a median follow-up time of 15.9 years, there were 2121 cases of hip fractures and 28 718 cases of total fractures. Women scoring in the highest quintile (Q5) of the aMED index had a lower risk for hip fractures (HR, 0.80; 95% CI, 0.66-0.97), with an absolute risk reduction of 0.29% and a number needed to treat of 342 (95% CI, 249-502). No association between the aMED score and total fractures was observed (Q5 HR, 1.01; 95% CI, 0.95-1.07). Higher HEI-2010 or DASH scores tended to be inversely related to hip fracture risk, but the results were nonsignificant (Q5 HR, 0.87; 95% CI, 0.75-1.02; and Q5 HR, 0.89; 95% CI, 0.75-1.06, respectively). The AHEI-2010 score was associated with neither hip nor total fractures.

Conclusions and Relevance  Higher adherence to a Mediterranean diet is associated with a lower risk for hip fractures. These results support that a healthy dietary pattern may play a role in maintaining bone health in postmenopausal women.

 

dott.ssa Vincenza De Falco
Specialista in Ginecologia e Ostetricia

INFORMAZIONI E PRENOTAZIONI

Dieta Mediterranea: reduce il rischio di fratture dell’anca da osteoporosi